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Formation of Blood Clots

Life & Health

★Exhibit Content: Thrombosis Knowledge ★Interaction: Electromechanical Interaction ★Operation: 1. Rotate the main valve to start the liquid flow in the pipeline; 2. Rotate the small handle to connect the pipeline with or without thrombus, and observe the liquid flow status in the pipeline under the conditions with and without thrombus. ★Exhibit Description: The exhibit consists of a display wall and an interactive thrombosis model. A set of connected transparent pipes is installed on the display wall, with liquid inside. At one point, two pipes are connected in parallel: one contains liquid with blood clots (simulating thrombosis), and the other contains normal liquid (simulating no thrombosis), controlled by a small valve rotary handle; another point has a main valve rotary handle. The entire system uses a booster pump to circulate the liquid, simulating the flow of human blood under a certain blood pressure. Rotate the main valve to start the liquid flow in the pipes. By rotating the small handle, connect the pipe with or without thrombus and observe the liquid flow status in the pipeline under the conditions with and without thrombus. ★Scientific Principle: A thrombus is a "blood clot" formed by blood coagulation within blood vessels. Its formation is mainly based on three factors: vascular injury, abnormal blood flow, and changes in blood composition. Normally, the vascular endothelium is smooth and anticoagulant. When blood vessels are damaged (such as plaque rupture), subendothelial collagen is exposed, and platelets rapidly adhere and aggregate to form a "white thrombus" that temporarily plugs the gap. At the same time, the coagulation system is activated, and thrombin converts soluble fibrinogen into an insoluble fibrin network, trapping a large number of red blood cells and white blood cells to form a stable "red thrombus," completely blocking the blood vessel. Slow blood flow (such as prolonged bed rest) or hypercoagulability (such as dehydration, hyperlipidemia) greatly promotes this process. If a thrombus dislodges, it may cause myocardial infarction, cerebral infarction, or pulmonary embolism.

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